Co-Catalyzed Synthesis of N-Sulfonylcarboxamides from Carboxylic Acids and Sulfonyl Azides,The Journal of Organic Chemistry

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Co-Catalyzed Synthesis of N-Sulfonylcarboxamides from Carboxylic Acids and Sulfonyl Azides
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2018-06-29 00:00:00 , DOI: 10.1021/acs.joc.8b01300
Yue Fang _{1,

2,

3} , Zheng-Yang Gu ₂ , Shun-Yi Wang ₂ , Jin-Ming Yang ₁ , Shun-Jun Ji ₂

Affiliation

A Co-catalyzed effective synthesis of N-sulfonylcarboxamides from the reaction of carboxylic acids and organic azides in the presence of isocyanide has been developed. The protocol has the advantages of short time, low temperature, and being oxidant-free, which provides a new and simple approach for the synthesis of N-sulfonylcarboxamides in good to excellent yields with a broad substrate scope.

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