Here, the morphology of polypore fungi has inspired the fabrication of poly(vinylidene fluoride) (PVDF) membranes with dual porosity by nonsolvent-induced phase separation (NIPS). The fruiting body of such microorganisms is constituted of two distinct regions, finger- and sponge-like structures, which have been successfully mimicked by controlling the coagulation bath temperature during the NIPS process. The use of water at 10 °C as coagulant resulted in membranes with the highest finger-like/sponge-like ratio (53% of the total membrane thickness), while water at 90 °C allowed the formation of macrovoid-free membranes. The microchannels and the asymmetric porosity were used to enhance the oil sorption capacity of the PVDF membranes and to achieve directional release of therapeutic essential oils. These PVDF membranes with easily tuned asymmetric channel-like porosity and controlled pore size are ideal candidates for drug delivery applications.

中文翻译：

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生物启发的聚偏氟乙烯膜，可定向释放治疗性精油

在这里，多孔真菌的形态激发了通过非溶剂诱导相分离（NIPS）形成具有双重孔隙率的聚偏二氟乙烯（PVDF）膜的制造。这种微生物的子实体由两个不同的区域组成，即手指状和海绵状结构，通过在NIPS过程中控制凝固浴的温度已成功地模仿了这些区域。在10°C的水用作凝结剂时，膜的手指状/海绵状比率最高（占总膜厚度的53％），而在90°C的水则可形成无大孔的膜。使用微通道和不对称孔隙率可提高PVDF膜的吸油能力，并实现治疗性香精油的定向释放。