Invasive squamous cell carcinoma (SCC) of the penis is almost always treated with surgical therapy at the primary site. However, almost all other SCC primary sites, such as anal, vulvar, uterine cervix, head and neck, and oesophagus, and their involved nodal basins, can be successfully treated with radiotherapy or combined chemotherapy and radiation, reserving surgery as a salvage option. Review of the penile cancer literature and examination of data from more common SCC primary sites make a case for complete organ preservation of the penis using definitive combined chemotherapy and radiation, reserving surgical therapies as salvage options.

中文翻译：

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非转移性阴茎癌的非手术治疗

阴茎浸润性鳞状细胞癌（SCC）几乎总是在原发部位进行外科手术治疗。但是，几乎所有其他SCC原发部位，例如肛门，外阴，子宫颈，头颈部和食道及其累及的淋巴结盆，都可以成功地通过放疗或化学疗法和放射疗法联合治疗，保留外科手术作为挽救选择。回顾阴茎癌文献并检查来自更常见的SCC原发部位的数据，可以证明使用确定的联合化学疗法和放射线将阴茎完全保存起来，保留手术疗法作为挽救选择。