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Metal‐Free Synthesis of Furocoumarins: An Approach via Iodine‐Promoted One‐Pot Cyclization between 4‐Hydroxycoumarins and Acetophenones
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2018-08-16 , DOI: 10.1002/ejoc.201800983
Phuc H. Pham 1 , Que T. D. Nguyen 1 , Nhu K. Q. Tran 1 , Vu H. H. Nguyen 1 , Son. H. Doan 1 , Hiep Q. Ha 1 , Thanh Truong 1 , Nam T. S. Phan 1
Affiliation  

An iodine‐mediated one‐pot synthesis of furocoumarins has been developed. The furocoumarins were obtained in high yields in the presence of NH4OAc as an additive, whereas neither acidic nor basic additives were effective.
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中文翻译:

呋喃香豆素的无金属合成:通过碘促进的4-羟基香豆素和乙酰苯之间的一锅环化的方法。

已经开发了碘介导的呋喃香豆素的一锅法合成法。在存在NH 4 OAc作为添加剂的情况下,以高收率获得了呋喃香豆素,而酸性和碱性添加剂均无效。
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更新日期:2018-08-16
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