Levulinic acid is produced from the acidic aqueous degradation of 5-hydroxymethylfurfural, with potential applications in bio-value added chemicals synthesis. Here, we report for the first time, the Baeyer-Villiger oxidation of levulinic acid to succinic acid, with hydrogen peroxide and tungstic acid at mild conditions and without any organic solvent. We investigated the effects of time, amount of reagent-to-catalyst molar ratio and H₂O₂-to-levulinic acid molar ratio. The maximum succinic acid selectivity was 75% with a levulinic acid conversion as high as 48%, after 6 h at 90 °C. We propose a reaction mechanism based on results obtained from the reactivity of the intermediates. The catalyst interacts with the substrate, forming a cyclic species that enhances the formation of succinic acid versus 3-hydroxypropanoic acid.

戊酸是由5-羟甲基糠醛的酸性水溶液降解产生的，在生物增值化学品合成中具有潜在的应用。在这里，我们首次报道了在温和的条件下，没有任何有机溶剂的情况下，过氧化氢和钨酸将乙酰丙酸的Baeyer-Villiger氧化为琥珀酸。我们研究了时间，试剂与催化剂的摩尔比和H ₂ O _{2量的影响}-乙酰丙酸摩尔比。在90°C下放置6小时后，最大琥珀酸选择性为75％，乙酰丙酸转化率高达48％。我们基于从中间体的反应性获得的结果提出了一种反应机理。催化剂与底物相互作用，形成环状物质，与3-羟基丙酸相比，环状物质增强了琥珀酸的形成。