Along with the vigorous development of hypervalent iodine chemistry, water-soluble hypervalent iodine reagents have received considerable attentions in recent years. In order to obtain water-soluble hypervalent iodine reagents, two strategies have been employed including introduction of hydrophilic functional groups onto the phenyl ring and formation of complex of iodosylbenzene with crown ether. And, it is observed that four kinds of hypervalent iodine reagents exhibit more or less solubility in water including hypervalent iodine reagents containing hydrophilic ligands, diaryliodonium salts, oligomeric iodosylbenzene sulfate, and iodylbenzene and its derivatives. In this review, we summarize these water-soluble hypervalent iodine reagents and their broad synthetic applications in aqueous media.

随着高价碘化学的蓬勃发展，水溶性高价碘试剂近年来受到了相当大的关注。为了获得水溶性高价碘试剂，已经采用了两种策略，包括将亲水性官能团引入到苯环上以及形成碘基苯与冠醚的配合物。并且，观察到四种高价碘试剂在水中表现出或多或少的溶解性，包括含有亲水性配体的高价碘试剂，二芳基碘鎓盐，低聚碘基苯硫酸盐和碘基苯及其衍生物。在这篇综述中，我们总结了这些水溶性高价碘试剂及其在水性介质中的广泛合成应用。