Synthesis ( IF 2.2 ) Pub Date : 2018-06-25 , DOI: 10.1055/s-0037-1610170 Cherif Behloul 1 , Francisco Foubelo 2, 3, 4 , Meriem Benlahrech 1 , Carmen Nájera 2, 4 , Miguel Yus 2, 4
Dedicated to Professor Vicente Gotor on the occasion of his retirement
Abstract
5-Substituted 1-benzyltetrazoles are easily debenzylated to give the corresponding deprotected tetrazoles using dissolved metals under protic conditions: Mg/MeOH, In/MeOH, or Zn/MeCO2H are the procedures of choice for this transformation.
5-Substituted 1-benzyltetrazoles are easily debenzylated to give the corresponding deprotected tetrazoles using dissolved metals under protic conditions: Mg/MeOH, In/MeOH, or Zn/MeCO2H are the procedures of choice for this transformation.
中文翻译:
受保护的1H-四唑的铟,镁和锌介导的脱苄基作用:对比研究
退职时奉献给维森特·戈托尔(Vicente Gotor)教授
抽象的
在质子条件下,使用溶解的金属可以轻松地将5-取代的1-苄基四唑脱苄基,得到相应的脱保护四唑:Mg / MeOH,In / MeOH或Zn / MeCO 2 H是该转化的选择方法。
在质子条件下,使用溶解的金属可以轻松地将5-取代的1-苄基四唑脱苄基,得到相应的脱保护四唑:Mg / MeOH,In / MeOH或Zn / MeCO 2 H是该转化的选择方法。