Management of postoperative pain following bone surgery includes administration of local anesthetics (LAs). Smart delivery systems, including triggered systems, have been designed to provide a continuous release of LA in situ. However, these systems can provide a high level of LA locally. This review will examine the state-of-the-art regarding the LA delivery systems optimized for management of postoperative pain in bone surgery and will discuss the potential adverse effects of LAs on the overall pathways of bone healing, including the inflammation response phase, hemostasis phase, tissue repair phase and remodeling phase. There is a clinical need to document these effects and the potential impacts on the clinical outcome of the patient.

骨手术后的术后疼痛管理包括局部麻醉药（LAs）的管理。设计了包括触发系统在内的智能交付系统，以提供原位LA的连续释放。但是，这些系统可以在本地提供高级别的LA。这篇综述将探讨最优化用于骨外科手术后疼痛管理的LA输送系统的最新技术，并将讨论LA对骨愈合总体路径的潜在不利影响，包括炎症反应阶段，止血阶段，组织修复阶段和重塑阶段。临床上需要记录这些影响以及对患者临床结果的潜在影响。