Tungstic acid-functionalized MCM-41 (MCM-41–HWO₄) was prepared, characterized and applied as a reusable mesoporous catalyst for the one-pot synthesis of new pyrrolo[2,1-a]isoquinoline derivatives. The characterization was performed using FT-IR, X-ray diffraction patterns (XRD), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). Pyrrolo[2,1-a]isoquinolines were prepared in the presence of this novel MCM-41 based nanocatalyst via the four-component reaction of arylaldehydes, Meldrum's acid, isoquinoline and alkyl isocyanides. MCM-41–HWO₄ is a low-cost and nontoxic heterogeneous catalyst which provides green reaction conditions. Additionally, it can be reused many times without a significant loss of activity.

中文翻译：

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钨酸官能化的MCM-41作为新型介孔固体酸催化剂，用于一锅合成新的吡咯并[2,1- a ]异喹啉†

制备了钨酸官能化的MCM-41（MCM-41–HWO ₄），并将其表征为可重复使用的介孔催化剂，用于一锅合成新的吡咯并[2,1- a ]异喹啉衍生物。使用FT-IR，X射线衍射图谱（XRD），扫描电子显微镜（SEM）和能量色散X射线光谱仪（EDX）进行表征。在这种新颖的基于MCM-41的纳米催化剂的存在下，通过芳醛，Meldrum的酸，异喹啉和烷基异氰化物的四组分反应制备了吡咯并[2,1- a ]异喹啉。MCM-41–HWO ₄是一种低成本且无毒的非均相催化剂，可提供绿色反应条件。此外，它可以重复使用很多次，而不会造成重大活动损失。