Shaping molecular diversity

Shaping molecular diversity, Published online: 21 June 2018; doi:10.1038/s41557-018-0095-7

Certain drug targets have been deemed undruggable because of the difficulty in finding pharmacologically useful inhibitors. Now, two teams have developed exciting technologies for the creation of diverse collections of macrocyclic molecules and have demonstrated their usefulness for discovering macrocyclic inhibitors.

中文翻译：

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塑造分子多样性

塑造分子多样性

塑造分子多样性，在线发布：2018年6月21日; doi：10.1038 / s41557-018-0095-7

由于难以找到药理学上有用的抑制剂，某些药物靶标被认为是不可药物的。现在，两个团队开发了令人兴奋的技术来创建各种大环分子集合，并证明了它们对发现大环抑制剂的有用性。