Herein we report an unprecedented reaction between substituted salicylaldehydes and SCDA to furnish 2,2-difluoro-2,3-dihydrobenzofuran-3-ols. The reaction is highly effective for a range of diverse salicylaldehydes bearing meta-electron-withdrawing substituents. Of particular interest was the discovery that the requirement for a base in the occurred reaction directly correlated with the pKa of the substrates used.

中文翻译：

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原位分子内二氟卡宾引发的2 - gem -difluoro-2,3-dihydrobenzofuran-3-ols的合成

在本文中，我们报道了取代的水杨醛与SCDA之间的空前反应，以提供2,2-二氟-2,3-二氢苯并呋喃-3-醇。对于一系列带有间吸电子取代基的水杨醛，该反应非常有效。特别令人感兴趣的发现是，发生的反应中对碱的需求与所用底物的pKa直接相关。