A paper spray mass spectrometry (PS-MS) method has been developed for the rapid quantification of benzoic acid (BA) and vitamin C (VC) in beverages. Using BA-d5 as an internal standard (IS) to analyze BA and VC, the calibration curves ranged from 0.3 to 100 μg/mL for BA and 1 to 100 μg/mL for VC, the linearity was 0.9996 for BA and 0.9973 for VC. The limits of detection (LODs) and limits of quantitation (LOQs) were 0.1 μg/mL and 0.3 μg/mL for BA, 0.3 μg/mL and 1 μg/mL for VC, respectively. The recovery ranged from 91.1 to 106.7% for BA, 92.6 to 108.2% for VC. Compared with HPLC, there is no substantial difference in the quantification of BA and VC in samples, the accuracy was 95.7–102.2%, and the run time is far less than that of the HPLC method. The results indicated that PS-MS is a rapid, environmentally friendly and high-throughput method for the quantification of BA and VC.

为了快速定量饮料中的苯甲酸（BA）和维生素C（VC），已经开发了一种纸喷雾质谱（PS-MS）方法。使用BA-d5作为内标（IS）分析BA和VC，BA的校准曲线范围为0.3至100μg/ mL，VC的校准曲线范围为1至100μg/ mL，BA的线性为0.9996，VC的线性为0.9973 。BA的检出限（LOD）和定量限（LOQ）分别为VC为0.3μg/ mL和0.3μg/ mL，而VC为1μg/ mL。BA的回收率介于91.1％至106.7％之间，VC的回收率介于92.6％至108.2％之间。与HPLC相比，样品中BA和VC的定量没有实质性差异，准确度为95.7–102.2％，并且运行时间远远少于HPLC方法。结果表明PS-MS是一种快速，