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Solventless triarylmethane synthesis via hydroxyalkylation of anisole with benzaldehyde by modified heteropoly acid on mesocellular foam silica (MCF)
Molecular Catalysis ( IF 4.6 ) Pub Date : 2018-06-15 , DOI: 10.1016/j.mcat.2018.06.003
Kalpesh H. Bhadra , Ganapati D. Yadav

Triarylmethane (TRAM) compounds have wide applications such as leuco dyes for sensing tumors and other biological activities. Hydroxyalkylation of arenes with benzaldehyde results in formation of triarylmethane compounds. In the present study, 20 (wt.%) Cs2.5H0.5PW12O40 (Cs-DTP) supported on mesocellular foam (MCF) silica was prepared, characterized and tested for its activity in hydroxyalkylation reaction of anisole with benzaldehyde. Its activity was compared with commercial catalysts like Amberlyst-15, montmorillonite clay K-10, H3PW12O40 and unsupported Cs2.5H0.5PW12O40.The prepared catalyst showed the best activity compared to others with advantage of separation of catalyst and reusability. Reaction parameters were studied in detail and kinetic study was carried out for the said reaction. 20 (wt. %) Cs-DTP/MCF was found to be the best, robust and reusable catalyst. Reaction mechanism and kinetics were also studied. The results are new.



中文翻译:

在介孔泡沫二氧化硅(MCF)上通过改性杂多酸通过苯甲醚与苯甲醛的羟烷基化合成无溶剂三芳基甲烷

三芳基甲烷(TRAM)化合物具有广泛的应用,例如用于感测肿瘤和其他生物活性的无色染料。芳烃与苯甲醛的羟烷基化导致形成三芳基甲烷化合物。在本研究中,制备了负载在介孔泡沫(MCF)二氧化硅上的20(wt。%)Cs 2.5 H 0.5 PW 12 O 40(Cs-DTP),表征并测试了其在苯甲醚与苯甲醚的羟烷基化反应中的活性。将其活性与市售催化剂(如Amberlyst-15,蒙脱土K-10,H 3 PW 12 O 40和无载体Cs 2.5 H 0.5 PW 12 O)进行了比较。40.与其他催化剂相比,制得的催化剂具有最佳的活性,具有分离催化剂和可重复使用的优点。详细研究了反应参数,并对该反应进行了动力学研究。发现20(wt。%)的Cs-DTP / MCF是最好的,坚固的和可重复使用的催化剂。还研究了反应机理和动力学。结果是新的。

更新日期:2018-06-15
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