l‐Valine diethyl amide is the chiral auxiliary of choice to prepare optically active aminodecalone scaffolds with quaternary stereocenter by enantioselective copper‐catalyzed Michael reaction followed by Robinson annulation. Intermediate products were further submitted to Fischer indole and Friedländer quinoline annulation.

中文翻译：

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氨基癸酮支架–对映选择性合成，吲哚和喹啉环化

l-缬氨酸二乙酰胺是选择的手性助剂，可通过对映选择性的铜催化Michael反应，然后进行Robinson环合反应来制备具有四级立体中心的旋光性氨基癸酮支架。中间产品进一步提交给了Fischer吲哚和Friedländer喹啉环化法。