Abstract Viscoelastic gels of xanthan gum-chitosan(X-Ch) in formic acid were electrospun to produce nanofibers, stable in aqueous media, for the encapsulation and release of curcumin (Cu). After 120 h, the nanofibers released lower amount of curcumin (∼20%) at pH 2.2 comparatively to the release in neutral media (∼50%), suggesting that X-Ch nanofibers could be used as a carrier for the encapsulation of hydrophobic bioactive compounds with long-term pH-stimulated release properties.

中文翻译：

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静电纺黄原胶-壳聚糖纳米纤维作为疏水性生物活性物质的递送载体

摘要 黄原胶-壳聚糖（X-Ch）在甲酸中的粘弹性凝胶通过电纺制备纳米纤维，在水性介质中稳定，用于封装和释放姜黄素（Cu）。120 小时后，与在中性介质中的释放量（~50%）相比，纳米纤维在 pH 2.2 时释放的姜黄素量（~20%）较低，这表明 X-Ch 纳米纤维可用作包封疏水性生物活性物质的载体。具有长期 pH 刺激释放特性的化合物。