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Access to sulfonylated furans or imidazo[1,2-a]pyridines via a metal-free three-component, domino reaction†
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2018-06-14 00:00:00 , DOI: 10.1039/c8qo00443a
Zhiming Cui 1, 2, 3, 4 , Baofu Zhu 1, 2, 3, 4 , Xuechen Li 5, 6, 7, 8 , Hua Cao 1, 2, 3, 4
Affiliation  

An efficient three-component reaction of 1,3-dicarbonyl compounds or pyridin-2-amines with ynals and sodium benzenesulfinates has been developed. This domino process provides a new and effective strategy for the preparation of sulfonylated furan or imidazo[1,2-a]pyridine derivatives. The strategy exhibits excellent functional group tolerance and good efficiency.

中文翻译:

访问磺酰喃或咪唑并[1,2]吡啶通过金属-自由三组分,多米诺反应

已经开发出有效的三组分1,3-二羰基化合物或吡啶-2-胺与乙醛和苯磺酸钠的反应。该多米诺法为磺酰化呋喃或咪唑并[1,2- a ]吡啶衍生物的制备提供了一种新的有效策略。该策略表现出出色的功能组耐受性和良好的效率。
更新日期:2018-06-14
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