Access to sulfonylated furans or imidazo[1,2-a]pyridines via a metal-free three-component, domino reaction†,Organic Chemistry Frontiers

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Access to sulfonylated furans or imidazo[1,2-a]pyridines via a metal-free three-component, domino reaction†
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2018-06-14 00:00:00 , DOI: 10.1039/c8qo00443a
Zhiming Cui _{1,

2,

3,

4} , Baofu Zhu _{1,

2,

3,

4} , Xuechen Li _{5,

6,

7,

8} , Hua Cao _{1,

2,

3,

4}

Affiliation

An efficient three-component reaction of 1,3-dicarbonyl compounds or pyridin-2-amines with ynals and sodium benzenesulfinates has been developed. This domino process provides a new and effective strategy for the preparation of sulfonylated furan or imidazo[1,2-a]pyridine derivatives. The strategy exhibits excellent functional group tolerance and good efficiency.

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