Substituted 1,2,3‐triazoles are important heterocyclic molecules with applications in diverse research areas. The organocatalytic (3+2) cycloaddition reaction of azides with active methylene compounds has proven to be a powerful strategy for the synthesis of a variety of 1,2,3‐triazoles with different substituents. However the reported methods in the literature, commonly used a homogenous organocatalyst. Considering this point, here we have reported a novel heterogeneous protocol for the synthesis of 1,4,5‐trisubstituted 1,2,3‐triazoles by reaction of different dicarbonyl compounds with aryl azides catalyzed by copper oxide nanoparticles under microwave irradiation. The important features of this methodology are high yield products, short reaction times and recyclability of the CuO catalyst.

中文翻译：

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CuO纳米颗粒是一种高效的多相催化剂，可将二羰基化合物与叠氮化物进行1,3-偶极环加成反应

取代的1,2,3-三唑是重要的杂环分子，在不同的研究领域中都有应用。叠氮化物与活性亚甲基化合物的有机催化（3 + 2）环加成反应已被证明是合成各种具有不同取代基的1,2,3-三唑的有效策略。然而，文献中报道的方法通常使用均相有机催化剂。考虑到这一点，在这里我们报道了一种新颖的异构协议，该协议通过微波辐射下不同的二羰基化合物与氧化铜纳米颗粒催化的芳基叠氮化物的反应来合成1,4,5-三取代的1,2,3-三唑。该方法的重要特征是高收率的产品，较短的反应时间和CuO催化剂的可回收性。