Core-shell nanostructured materials, which are of great interest for fundamental research and industrial applications, have properties that can be enhanced by combining component superstructures. Here, we report the new construction of magnetic core-shell gold nanostars (AuNSs) for controlled release of drug. The AuNSs were successfully embedded intact between an inner silica layer and outside mesoporous silica layer to create magnetic core/shell hybrid nanoparticles by using a base cationic templating surfactant, cetyltrimethylammonium hydroxide (CTAOH). The core-shell nano-composites containing AuNSs exhibit the characteristics including high magnetization, mesoporous nanostructure, photothermal properties and low in vitro toxicity, showing the potential applications for drug delivery and controlled release.

核壳纳米结构材料对基础研究和工业应用非常感兴趣，其性能可以通过组合组件上层结构来增强。在这里，我们报告了用于药物控制释放的磁性核-壳金纳米星（AuNSs）的新结构。通过使用碱性阳离子模板表面活性剂十六烷基三甲基氢氧化铵（CTAOH），将AuNS成功完整地嵌入到内部二氧化硅层和外部中孔二氧化硅层之间，以创建磁性核/壳杂化纳米粒子。含有AuNS的核-壳纳米复合材料具有高磁化强度，中孔纳米结构，光热特性和低体外毒性等特征，显示了药物递送和控释的潜在应用。