Fat busters: Nonalcoholic fatty liver disease, which is characterized by excess accumulation of triglyceride in hepatocytes, is the major cause of chronic liver disease worldwide and no approved drug is available. Therefore, small molecules that decrease lipogenesis and lipid accumulation in hepatocytes by inhibiting the mechanistic target of rapamycin (mTOR) pathway have been developed.

中文翻译：

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喹啉-拟模拟物可减少肝细胞的脂质生成和脂质蓄积

脂肪克星：非酒精性脂肪性肝病，其特征是肝细胞中甘油三酸酯过多积聚，是全世界慢性肝病的主要原因，目前尚无批准的药物。因此，已经开发出通过抑制雷帕霉素（mTOR）途径的机械靶来减少肝细胞中脂肪生成和脂质积累的小分子。