The glycated fish protein (GP) was fed to rats to firstly evaluate their impacts on gut health. The rats were fed fish protein (FP) diet, heated fish protein (HP) diet, GP diet or AIN-93G (SD) diet for two weeks. Compared with FP diet, GP diet significantly reduced body weight gains in rats (p < 0.05), showed the weaker intensity of protein fermentation in large intestine of rats, and also considerably increased the butyrate level, which was closely related to the formation of fructoselysine via the glycation of FP. The cecal bacterial communities in rats fed GP diet indicated a great abundance of Allobaculum, Akkermansia, Turicibacter and Lactobacillus animalis, while a low abundance of Escherichia-Shigella, Fusobacterium and Erysipelatoclostridium. The abundance of Collinsella, Allobaculum and Ruminococcaceae_UCG-014 was significantly positively correlated with the production of butyrate. Overall, glycated protein enriched in Amadori products may have a potential beneficial effect on gut health.

将糖化鱼蛋白（GP）喂给大鼠，首先评估它们对肠道健康的影响。给大鼠喂鱼蛋白（FP）饮食，加热鱼蛋白（HP）饮食，GP饮食或AIN-93G（SD）饮食两周。与FP饮食相比，GP饮食显着降低了大鼠的体重增加（p <0.05），显示了大鼠大肠中蛋白质发酵的强度较弱，并且丁酸水平也显着提高，这与果糖赖氨酸的形成密切相关。通过FP糖基化。饲喂GP饮食的大鼠盲肠细菌群落显示出大量的异常杆菌，Akkermansia，Turicibacter和Lactobacillus animalis，而少量的Escherichia-Shigella，梭菌和嗜热芽孢杆菌。丰柯林斯，Allobaculum和Ruminococcaceae_UCG-014是显著积极与生产丁酸的相关性。总体而言，富含Amadori产品的糖化蛋白可能对肠道健康有潜在的有益影响。