当前位置: X-MOL 学术J. Funct. Foods › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Microbiome and butyrate production are altered in the gut of rats fed a glycated fish protein diet
Journal of Functional Foods ( IF 3.8 ) Pub Date : 2018-06-12 , DOI: 10.1016/j.jff.2018.06.007
Kaining Han , Weiya Jin , Zhenjie Mao , Shiyuan Dong , Qi Zhang , Yuhong Yang , Bingcan Chen , Haohao Wu , Mingyong Zeng

The glycated fish protein (GP) was fed to rats to firstly evaluate their impacts on gut health. The rats were fed fish protein (FP) diet, heated fish protein (HP) diet, GP diet or AIN-93G (SD) diet for two weeks. Compared with FP diet, GP diet significantly reduced body weight gains in rats (p < 0.05), showed the weaker intensity of protein fermentation in large intestine of rats, and also considerably increased the butyrate level, which was closely related to the formation of fructoselysine via the glycation of FP. The cecal bacterial communities in rats fed GP diet indicated a great abundance of Allobaculum, Akkermansia, Turicibacter and Lactobacillus animalis, while a low abundance of Escherichia-Shigella, Fusobacterium and Erysipelatoclostridium. The abundance of Collinsella, Allobaculum and Ruminococcaceae_UCG-014 was significantly positively correlated with the production of butyrate. Overall, glycated protein enriched in Amadori products may have a potential beneficial effect on gut health.



中文翻译:

饲喂糖化鱼蛋白饮食的大鼠的肠道中微生物组和丁酸盐的产生发生了改变

将糖化鱼蛋白(GP)喂给大鼠,首先评估它们对肠道健康的影响。给大鼠喂鱼蛋白(FP)饮食,加热鱼蛋白(HP)饮食,GP饮食或AIN-93G(SD)饮食两周。与FP饮食相比,GP饮食显着降低了大鼠的体重增加(p <0.05),显示了大鼠大肠中蛋白质发酵的强度较弱,并且丁酸水平也显着提高,这与果糖赖氨酸的形成密切相关。通过FP糖基化。饲喂GP饮食的大鼠盲肠细菌群落显示出大量的异常杆菌AkkermansiaTuricibacterLactobacillus animalis,而少量的Escherichia-Shigella梭菌嗜热芽孢杆菌。丰柯林斯Allobaculum和Ruminococcaceae_UCG-014是显著积极与生产丁酸的相关性。总体而言,富含Amadori产品的糖化蛋白可能对肠道健康有潜在的有益影响。

更新日期:2018-06-12
down
wechat
bug