Beneficial effects produced by polyphenolic compounds are used in the treatment of various diseases, including diabetes. Thus it is relevant to investigate the protective effect of lingonberry extract (LB) on the activities of nucleoside triphosphate diphosphohydrolase (NTPDase), 5’‐nucleotidase (5’‐NT), and adenosine deaminase (ADA); the density of A1, A2A, and P2×7 receptors; production of reactive species (RS); and the levels of thiobarbituric acid reactive substances (TBARS) in the cerebral cortex of streptozotocin‐induced diabetic rats.

中文翻译：

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越橘提取物通过调节嘌呤能系统和减少糖尿病大鼠的氧化应激提供神经保护作用。

多酚化合物产生的有益作用可用于治疗多种疾病，包括糖尿病。因此，有必要研究越橘提取物（LB）对核苷三磷酸二磷酸水解酶（NTPDase），5'-核苷酸酶（5'-NT）和腺苷脱氨酶（ADA）活性的保护作用；A1，A2A和P2×7受体的密度；产生反应性物质（RS）；以及链脲佐菌素诱发的糖尿病大鼠大脑皮层中硫代巴比妥酸反应性物质（TBARS）的水平。