Background

Mushrooms have been valuable as edible and medical provisions for humankind. It is attributed not only to the quality of their taste but also to their biological activities. The extracts, compounds, and metabolites have a lot of biological activities such as antidiabetic, antioxidative, antitumor, and anti-inflammatory effects. The potent anti-inflammatory activity is associated with a multitude of signaling pathways. However, there are a few review papers on the anti-inflammatory activity of mushrooms.

Scope and approach

Herein, the anti-inflammatory potential of mushroom is critically discussed using in vitro and animal models. Moreover, the mechanisms of anti-inflammatory activity are summarized. The current status of clinical studies evaluating anti-inflammatory activity of mushroom is also presented.

Key findings and conclusion

It is believed that insights about these advances may encourage researchers to discover new phytochemical components and further study specific bioactivities of mushroom.

中文翻译：

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深入了解食用和药用蘑菇的抗炎特性

背景

蘑菇作为人类可食用和可食用的食品很有价值。这不仅归因于它们的味道质量，还归因于其生物活性。提取物，化合物和代谢物具有许多生物活性，例如抗糖尿病，抗氧化，抗肿瘤和抗炎作用。有效的抗炎活性与多种信号通路相关。但是，有一些关于蘑菇的抗炎活性的评论文章。

范围和方法

本文中，使用体外和动物模型对蘑菇的抗炎潜力进行了严格的讨论。此外，总结了抗炎活性的机制。还介绍了评估蘑菇抗炎活性的临床研究的现状。

主要发现和结论

据信，有关这些进展的见解可能会鼓励研究人员发现新的植物化学成分并进一步研究蘑菇的特定生物活性。