Enantioseparation of Au20(PP3)4Cl4 Clusters with Intrinsically Chiral Cores,Angewandte Chemie International Edition

当前位置： X-MOL 学术 › Angew. Chem. Int. Ed. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Enantioseparation of Au20(PP3)4Cl4 Clusters with Intrinsically Chiral Cores
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2018-06-19 , DOI: 10.1002/anie.201805695
Yanfei Zhu _{1,

2} , Hui Wang ₁ , Kaiwei Wan _{1,

2} , Jun Guo _{1,

2} , Chunting He ₃ , Yue Yu ₄ , Luyang Zhao ₂ , Yin Zhang _{1,

2} , Jiawei Lv ₁ , Lin Shi ₁ , Renxi Jin ₄ , Xinxiang Zhang ₄ , Xinghua Shi ₁ , Zhiyong Tang ₁

Affiliation

Au₂₀(PP₃)₄Cl₄ (PP₃=tris(2‐(diphenylphosphino)ethyl) phosphine), abbreviated as Au₂₀, is the only Au nanocluster with an intrinsically chiral core without a chiral environment (chiral ligands or Au‐thiolate staples), making it a unique object to understand chiral evolution and explore chiral applications. Unfortunately, the synthesized Au₂₀ is racemic, and its enantiomers have not yet been separated. Herein, we report a supramolecular assembly strategy with α‐cyclodextrin (α‐CD) to afford enantiopure Au₂₀ in bulk, and an enantiomer excess (ee) value of as‐separated Au₂₀ of 97 %. As a result of its high purity, the distinctive optical activity of Au₂₀, which originates from electronic transitions confined in chiral cores, is fully explored. Theoretical studies reveals that the enantioseparation results from the preferential self‐assembly of α‐CD with organic ligands on the surface of right‐handed Au₂₀.

中文翻译：

具有固有手性核的Au20（PP3）4Cl4团簇的对映体分离

Au ₂₀（PP ₃）₄ Cl ₄（PP ₃ =三（2-（二苯基膦基）乙基）膦）（缩写为Au ₂₀）是唯一具有固有手性核心但没有手性环境（手性配体或Au-硫醇盐钉书钉），使其成为了解手性进化和探索手性应用的独特对象。不幸的是，合成的Au ₂₀是外消旋的，其对映异构体尚未分离。本文中，我们报道了使用α-环糊精（α-CD）的超分子组装策略，可批量提供对映纯Au ₂₀，以及分离后的Au ₂₀的对映体过量（ee）值97％。由于其高纯度，人们充分探索了Au ₂₀的独特光学活性，该活性源于手性核中的电子跃迁。理论研究表明，对映体的分离是由于α-CD与右手Au ₂₀表面上的有机配体的优先自组装所致。

更新日期：2018-06-19

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11