Biotechnology embraces various physical and chemical phenomena toward advancement of health diagnostics. Toward such advancement, detection of toxins plays an important role. Toxins produce severe health impacts on consumption with high mortality associated in acute cases. The most prominent route of infection and intoxication is through food matrices. Therefore, rapid detection of toxins at low concentrations is the need of modern diagnostics. Lateral flow immunoassays are one of the emergent and popularly used rapid detection technology developed for detecting various kinds of analytes. This review thus focuses on recent advancements in lateral flow immunoassays for detecting different toxins in agricultural food. Appropriate emphasis was given on how the labels, recognition elements, or detection strategy has laid an impact on improvement in immunochromatographic assays for toxins. The paper also discusses the gradual change in sensitivities and specificities of assays in accordance with the method of food processing used. The review concludes with the major challenges faced by this technology and provides an outlook and insight of ideas to improve it in the future.

中文翻译：

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横向流免疫测定法的最新进展：食品中毒素检测的旅程

生物技术包含各种物理和化学现象，以促进健康诊断的发展。为了这种进步，毒素的检测起着重要的作用。毒素对消费产生严重的健康影响，在急性病例中具有很高的死亡率。感染和中毒的最主要途径是通过食物基质。因此，现代诊断技术需要快速检测低浓度的毒素。横向流动免疫测定法是一种新兴的且广泛使用的快速检测技术，用于检测各种分析物。因此，本综述着重于侧向流免疫测定法在检测农业食品中不同毒素方面的最新进展。适当强调标签，识别元素，或检测策略已对毒素的免疫色谱分析的改进产生了影响。本文还讨论了根据所用食品加工方法的敏感性和特异性的逐步变化。回顾总结了该技术所面临的主要挑战，并提出了对未来改进技术的看法和见解。