The purpose of this study is to demonstrate the presence of three more receptors in mitochondria. Two N-methyl-d-aspartate receptor (NMDAR) subunits (NR1 and NR2B) are found by protein immunoblot and immunogold labeling in mitochondria fraction isolated from rat heart. These data allow supposing NMDAR presence and functioning in the inner mitochondrial membrane. There are no signs of receptor presence obtained in heart tissue lysate, that indicates the receptor localization exactly in mitochondria. The possible receptor functions discussed are its participation in calcium transport and in excitation-metabolism coupling. Besides, preliminary evidence is obtained of GABA_A and GABA_B receptors presence in heart mitochondria. One can surmise their role in metabolism regulation and their possible co-operation with NMDAR just as in the nervous system.

这项研究的目的是证明线粒体中存在三种其他受体。两个N-甲基- d -天冬氨酸受体（NMDAR）亚基（NR1和NR2B）通过蛋白免疫印迹和免疫标记在从大鼠心脏中分离线粒体级分中发现。这些数据允许假设NMDAR在线粒体内膜中存在并起作用。在心脏组织裂解物中没有发现受体存在的迹象，这表明受体恰好位于线粒体中。讨论的可能的受体功能是其参与钙转运和激发-代谢耦合。此外，初步获得了GABA _A和GABA _B的证据。心脏线粒体中存在受体。就像在神经系统中一样，人们可以推测它们在代谢调节中的作用以及它们与NMDAR的可能合作。