The conventional treatment of textile effluents is usually inefficient in removing azo dyes and can even generate more toxic products than the original dyes. The aim of the present study was to optimize the process factors in the degradation of Disperse Red 343 by Fenton and Fenton-like processes, as well as to investigate the ecotoxicity of the samples treated under optimized conditions. A Box–Behnken design integrated with the desirability function was used to optimize dye degradation, the amount of residual H₂O₂ [H₂O_2residual], and the ecotoxicity of the treated samples (lettuce seed, Artemia salina, and zebrafish in their early-life stages). Dye degradation was affected only by catalyst concentration [Fe] in both the Fenton and Fenton-like processes. In the Fenton reaction, [H₂O_2residual] was significantly affected by initial [H₂O₂] and its interaction with [Fe]; however, in the Fenton-like reaction, it was affected by initial [H₂O₂] only. A. salina mortality was affected by different process factors in both processes, which suggests the formation of different toxic products in each process. The desirability function was applied to determine the best process parameters and predict the responses, which were confirmed experimentally. Optimal conditions facilitated the complete degradation of the dye without [H₂O_2residual] or toxicity for samples treated with the Fenton-like process, whereas the Fenton process induced significant mortality for A. salina. Results indicate that the Fenton-like process is superior to the Fenton reaction to degrade Disperse Red 343.

纺织废水的常规处理通常无法有效去除偶氮染料，甚至会产生比原始染料更多的有毒产物。本研究的目的是优化芬顿和类芬顿过程降解分散红 343 的工艺因素，并研究在优化条件下处理的样品的生态毒性。结合期望函数的 Box-Behnken 设计用于优化染料降解、残留 H ₂ O ₂ [H ₂ O _{2 残留}] 的量以及处理样品（生菜籽、卤虫和斑马鱼）的生态毒性。生命早期阶段）。在芬顿和类芬顿过程中，染料降解仅受催化剂浓度 [Fe] 的影响。 Fenton反应中，[H ₂ O _{2 残留}]受初始[H ₂ O ₂ ]及其与[Fe]相互作用的显着影响；然而，在类芬顿反应中，它仅受初始[H ₂ O ₂ ]的影响。盐藻死亡率在两个过程中都受到不同过程因素的影响，这表明每个过程中形成了不同的有毒产物。应用意愿函数来确定最佳工艺参数并预测响应，并通过实验证实。对于用类芬顿过程处理的样品来说，最佳条件促进了染料的完全降解，没有[H ₂ O _{2 残留}]或毒性，而芬顿过程导致了盐藻的显着死亡率。结果表明，类 Fenton 过程在降解分散红 343 方面优于 Fenton 反应。