Paper Capillary Enables Effective Sampling for Microfluidic Paper Analytical Devices,ACS Sensors

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Paper Capillary Enables Effective Sampling for Microfluidic Paper Analytical Devices
ACS Sensors ( IF 8.2 ) Pub Date : 2018-06-06 00:00:00 , DOI: 10.1021/acssensors.8b00335
Jin-Wen Shangguan ₁ , Yu Liu ₁ , Sha Wang ₁ , Yun-Xuan Hou ₁ , Bi-Yi Xu ₁ , Jing-Juan Xu ₁ , Hong-Yuan Chen ₁

Affiliation

The paper capillary is introduced to enable effective sampling on microfluidic paper analytical devices. By coupling the macroscale capillary force of paper capillary and the microscale capillary forces of native paper, fluid transport can be flexibly tailored with proper design. Subsequently, a hybrid-fluid-mode paper capillary device was proposed which enables fast and reliable sampling in an arrayed form with less surface adsorption and bias for different components. The resulting device thus supports high-throughput, quantitative, and repeatable assays by manual operation. With all these merits, multiplex analysis of ions, proteins, and microbes have all been realized on this platform, which has paved the way to higher analysis on μPADs.

中文翻译：

纸毛细管能够为微流纸分析设备进行有效采样

引入纸毛细管是为了能够在微流纸分析设备上进行有效采样。通过将纸毛细管的宏观毛细管力与天然纸的微观毛细管力耦合，可以通过适当的设计灵活地调整流体的传输。随后，提出了一种混合流体模式纸毛细管装置，该装置能够以阵列形式进行快速可靠的采样，并且对不同的组分具有较少的表面吸附和偏压。因此，所得设备可通过手动操作支持高通量，定量和可重复的测定。具有所有这些优点，在该平台上已经实现了离子，蛋白质和微生物的多重分析，这为在μPAD上进行更高的分析铺平了道路。

更新日期：2018-06-06

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