This review characterizes the multicomponent reactions of acenaphthoquinone as building blocks for the synthesis of a variety of heterocyclic compounds with medicinal chemistry interest. There is a wide range of reactions that include acenaphthoquinone in the synthesis of heterocyclic compounds. Also this review gives an overview spirocyclic compounds has important applications in pharmacological during the period from 2000 to 2017. Spiro compounds having cyclic structures fused at a central carbon are of recent interest due to their interesting adjustable overall qualities and their structural implications on biological systems.

中文翻译：

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基于Ac醌的多组分反应的最新进展：螺ac烯化合物的合成

这篇综述将醌的多组分反应表征为合成具有医学化学意义的各种杂环化合物的基础。在杂环化合物的合成中存在各种各样的反应，包括苯醌。这篇综述还概述了螺环化合物在2000年至2017年期间在药理学中的重要应用。具有环结构稠合在中心碳原子上的螺环化合物由于其有趣的可调节总体质量及其对生物系统的结构意义而引起人们的关注。