Chronic non-healing wounds represent one of the most common complications of diabetes and need advanced treatment strategies. Exosomes are key mediators of cell paracrine action and can be directly utilized as therapeutic agents for tissue repair and regeneration. Here, we explored the effects of exosomes from human urine-derived stem cells (USC-Exos) on diabetic wound healing and the underlying mechanism.

中文翻译：

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来自人尿源性干细胞的外泌体DMBT1通过促进血管生成促进糖尿病伤口修复

慢性不愈合伤口代表糖尿病最常见的并发症之一，需要先进的治疗策略。外泌体是细胞旁分泌作用的关键介质，可以直接用作组织修复和再生的治疗剂。在这里，我们探讨了人类尿液衍生干细胞（USC-Exos）的外泌体对糖尿病伤口愈合的作用及其潜在机制。