Originally developed for the analysis of biological sequences, bioinformatics has advanced into one of the most widely recognized domains in the scientific community. Despite this technological evolution, there is still an urgent need for nontoxic and efficient drugs. The onus now falls on the ‘omics domain to meet this need by implementing bioinformatics techniques that will allow for the introduction of pioneering approaches in the rational drug design process. Here, we categorize an updated list of informatics tools and explore the capabilities of integrative bioinformatics in disease control. We believe that our review will serve as a comprehensive guide toward bioinformatics-oriented disease and drug discovery research.

生物信息学最初是为分析生物序列而开发的，现已发展成为科学界公认最广泛的领域之一。尽管技术发展，但仍然迫切需要无毒和有效的药物。现在，通过实施生物信息学技术来满足这一需求，责任就落在了“组学领域”，该技术将允许在合理的药物设计过程中引入开创性的方法。在这里，我们对信息学工具的更新列表进行分类，并探索整合生物信息学在疾病控制中的功能。我们相信，我们的评论将作为面向生物信息学的疾病和药物发现研究的综合指南。