A translation of the structure of mussel byssal threads into synthetic materials by the utilization of histidine-rich block copolymers†,Polymer Chemistry

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A translation of the structure of mussel byssal threads into synthetic materials by the utilization of histidine-rich block copolymers†
Polymer Chemistry ( IF 4.1 ) Pub Date : 2018-05-31 00:00:00 , DOI: 10.1039/c8py00663f
Marcel Enke _{1,

2,

3,

4,

5} , Ranjita K. Bose _{6,

7,

8,

9} , Stefan Zechel _{1,

2,

3,

4,

5} , Jürgen Vitz _{1,

2,

3,

4,

5} , Robert Deubler _{1,

2,

3,

4,

5} , Santiago J. Garcia _{6,

7,

8,

9} , Sybrand van der Zwaag _{6,

7,

8,

9} , Felix H. Schacher _{1,

2,

3,

4,

5} , Martin D. Hager _{1,

2,

3,

4,

5} , Ulrich S. Schubert _{1,

2,

3,

4,

5}

Affiliation

Mussel byssal threads are well-known due to their self-healing ability after the mechanical stress caused by waves. The proposed mechanism demonstrates the importance of reversible histidine–metal interactions as well as the block copolymer-like hierarchical architecture of the underlying protein structure. Taking these two aspects as inspiration for the design of synthetic analogs, different histidine-rich block copolymers were synthesized via reversible addition–fragmentation chain transfer (RAFT) polymerization. The hard domain was mimicked using polystyrene and the soft domain consists of n-butyl acrylate (BA) as well as histidine moieties as ligands. The block copolymers were crosslinked using different zinc(II) salts and the resulting metallopolymers were investigated with respect to their self-healing abilities. The observed two-step mechanism of the self-healing process was studied in detail. Furthermore, the mechanical properties were determined by nanoindentation and were correlated with other results.

中文翻译：

利用富含组氨酸的嵌段共聚物将贻贝的基底线结构转化为合成材料†

贻贝的掌骨线由于在波浪引起的机械应力后具有自愈能力，因此广为人知。所提出的机制证明了可逆的组氨酸-金属相互作用的重要性以及基础蛋白质结构的嵌段共聚物样递阶结构。以这两个方面为灵感，设计合成类似物，通过可逆的加成-断裂链转移（RAFT）聚合反应合成了不同的富含组氨酸的嵌段共聚物。使用聚苯乙烯模拟硬结构域，而软结构域由丙烯酸正丁酯（BA）以及组氨酸部分作为配体组成。使用不同的锌使嵌段共聚物交联（II研究了盐和所得的金属聚合物的自愈能力。详细研究了观察到的自我修复过程的两步机制。此外，机械性能是通过纳米压痕确定的，并与其他结果相关。

更新日期：2018-05-31

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