This paper reviews the potential of stilbenoids as nutraceuticals. Stilbenoid compounds in wine are considered key factors in health‐promoting benefits. Resveratrol and resveratrol‐related compounds are found in a large diversity of vegetal products. The stilbene composition varies from wine to wine and from one season to another. Therefore, the article also reviews how food science and technology and wine industry may help in providing wines and/or food supplements with efficacious concentrations of stilbenes. The review also presents results from clinical trials and those derived from genomic/transcriptomic studies. The most studied stilbenoid, resveratrol, is a very safe compound. On the other hand, the potential benefits of stilbene intake are multiple and are apparently due to downregulation more than upregulation of gene expression. The field may take advantage from identifying the mechanism of action(s) and from providing useful data to show evidence for specific health benefits in a given tissue or for combating a given disease.

中文翻译：

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白藜芦醇和相关的类胡萝卜素，具有健康促进作用的营养/饮食补充品：工业生产，安全性和寻找作用方式

本文综述了类胡萝卜素作为保健食品的潜力。葡萄酒中的类胡萝卜素化合物被认为是促进健康的关键因素。白藜芦醇和与白藜芦醇有关的化合物存在于多种植物产品中。wine的组成因葡萄酒的不同而不同，并且从一个季节到另一个季节也不同。因此，本文还回顾了食品科学技术和葡萄酒工业如何帮助提供具有有效浓度的斯蒂芬类物质的葡萄酒和/或食品补品。该评价还提供了来自临床试验的结果以及来自基因组/转录组研究的结果。研究最多的类胡萝卜素白藜芦醇是一种非常安全的化合物。另一方面，二苯乙烯的摄入的潜在益处是多重的，并且显然是由于基因表达的下调多于上调。