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Tensile biomechanical properties and constitutive parameters of human corneal stroma extracted by SMILE procedure
Journal of the Mechanical Behavior of Biomedical Materials ( IF 3.3 ) Pub Date : 2018-05-30 , DOI: 10.1016/j.jmbbm.2018.05.042
Yaoqi Xiang , Min Shen , Chao Xue , Di Wu , Yan Wang

The biomechanical behavior of human corneal stroma under uniaxial tension was investigated by the experimental analysis of cornea stromal lenticules taken out by corneal refractive surgery. Uniaxial tests were conducted to determine their stress-strain relationship and tensile strength. The Gasser-Ogden-Holzapfel (GOH) model was used to describe biomechanical behavior of the corneal stroma. The theoretical stress-strain relationship of the GOH model in the uniaxial tensile test was deduced. The corneal specimens were collected from ten patients (4 male and 6 female), aged from 17 to 36. The differences between corneal stress-strain relationship in the horizontal and vertical direction were compared. The constitutive parameters C10, k1 and k2 were evaluated through least squares curve-fitting of experimental data.



中文翻译:

SMILE法提取人角膜基质的拉伸生物力学性能和本构参数

通过对角膜屈光手术取出的角膜基质微透镜进行实验分析,研究了人角膜基质在单轴张力下的生物力学行为。进行单轴测试以确定它们的应力-应变关系和拉伸强度。Gasser-Ogden-Holzapfel(GOH)模型用于描述角膜基质的生物力学行为。推导了GOH模型在单轴拉伸试验中的理论应力-应变关系。收集了10位年龄在17至36岁的患者(男性4例,女性6例)的角膜标本。比较了水平和垂直方向上角膜应力-应变关系的差异。本构参数C 10k 1k通过最小二乘曲线拟合实验数据评估了2个。

更新日期:2018-05-30
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