Alzheimer's disease is a progressive neurodegenerative disease that involves loss of memory, thinking, and reasoning and several behavioral characteristics. Alzheimer's disease affects an individual in a drastic manner by exhibiting its impact on the individual's daily routine. A completely accurate diagnosis can be achieved only after the death of a patient by observing the plaques and tangles in the brain. Hence, it is important that researchers develop robust diagnostic tools for detecting Alzheimer's disease. Neurotransmitters are suitable biomarkers for various neurological disorders, such as Parkinson's disease, Alzheimer's disease, and depression. In recent years, various analytical techniques for the detection of neurotransmitters have emerged. In this review article, we discuss the recent trends of such techniques and their limitations in the detection of various biomarkers involved in Alzheimer's disease. Furthermore, we investigate the recent progress in nanotechnology-based methods and future perspectives for the detection of neurotransmitters.

阿尔茨海默氏病是一种进行性神经退行性疾病，涉及记忆力，思维和推理的丧失以及若干行为特征。阿尔茨海默氏病通过对个体的日常活动产生影响而对个体产生极大的影响。只有在患者死亡后才能通过观察大脑中的斑块和缠结来实现完全准确的诊断。因此，重要的是，研究人员必须开发出强大的诊断工具来检测阿尔茨海默氏病。神经递质是合适的各种神经系统疾病（例如帕金森氏病，阿尔茨海默氏病和抑郁症）的生物标志物。近年来，已经出现了用于检测神经递质的各种分析技术。在这篇综述文章中，我们讨论了这种技术的最新趋势及其在检测与阿尔茨海默氏病有关的各种生物标记物中的局限性。此外，我们调查了基于纳米技术的方法的最新进展以及检测神经递质的未来前景。