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Characterization of a NIR absorbing thienyl curcumin contrast agent for photoacoustic imaging.
Chemical Communications ( IF 4.3 ) Pub Date : 2018-06-14 , DOI: 10.1039/c8cc03727b Stephanie Bellinger 1 , Maryam Hatamimoslehabadi , Raymond E Borg , Jeffrey La , Peter Catsoulis , Farha Mithila , Chandra Yelleswarapu , Jonathan Rochford
Chemical Communications ( IF 4.3 ) Pub Date : 2018-06-14 , DOI: 10.1039/c8cc03727b Stephanie Bellinger 1 , Maryam Hatamimoslehabadi , Raymond E Borg , Jeffrey La , Peter Catsoulis , Farha Mithila , Chandra Yelleswarapu , Jonathan Rochford
Affiliation
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The synthesis and characterization of a bis(2-dimethylaminothien-5-yl)curcumin boron difluoride chromophore is presented. Photophysical, electrochemical and computational investigations establish the properties of its absorption in the Vis-NIR spectral range relative to established curcumin dyes. Application of this thienyl curcumin dye as a photoacoustic contrast agent is investigated against the dicarbocyanine Cy5 dye in the 675-735 nm excitation range.
中文翻译：
用于光声成像的近红外吸收噻吩姜黄素造影剂的表征。
介绍了双(2-二甲基氨基噻吩-5-基)姜黄素二氟化硼发色团的合成和表征。光物理、电化学和计算研究确定了其相对于已建立的姜黄素染料在可见光-近红外光谱范围内的吸收特性。在 675-735 nm 激发范围内研究了这种噻吩基姜黄素染料作为光声造影剂与二碳花青 Cy5 染料的对比。
更新日期：2018-05-28
中文翻译：
用于光声成像的近红外吸收噻吩姜黄素造影剂的表征。
介绍了双(2-二甲基氨基噻吩-5-基)姜黄素二氟化硼发色团的合成和表征。光物理、电化学和计算研究确定了其相对于已建立的姜黄素染料在可见光-近红外光谱范围内的吸收特性。在 675-735 nm 激发范围内研究了这种噻吩基姜黄素染料作为光声造影剂与二碳花青 Cy5 染料的对比。
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