Abstract This work reports a non-enzymatic amperometric sensor for hydrogen peroxide based on the use of a glassy carbon composite electrode modified with core-shell Cu@PtPd/C nanoparticles. Cu@PtPd/C presents an important electrocatalytic activity towards hydrogen peroxide reduction. The comparison of the sensitivities and the charge transfer resistances for hydrogen peroxide at the glassy carbon composite electrode modified with 5.0% w/w Pt/C, Pd/C, Pd/C + Pt/C and Cu@PtPd/C demonstrate a clear synergism on the catalytic reduction of hydrogen peroxide at −0.100 V when having Pt, Pd and Cu incorporated in the core-shell nanostructure. The best compromise between sensitivity, reproducibility and response time was reached with 20.0% w/w Cu@PtPd/C. For the selected sensor (glassy carbon composite electrode containing 20.0% w/w GCPE/Cu@PtPd/C) the analytical parameters are highly competitive compared to similar devices reported in the last years, with a linear relationship between current and hydrogen peroxide concentration between 5.0 × 10−6 and 2.5 × 10−4 M, sensitivity of (5.30 ± 0.09) × 105 μAM−1 cm−2 (r2 = 0.998) and detection limit of (3.7 ± 0.5) × 10−7 M. The resulting sensing platform was successfully used for the quantification of hydrogen peroxide in a mouth-wash sample.

中文翻译：

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Cu@PtPd/C纳米颗粒在过氧化氢定量中的分析应用

摘要 本工作报告了一种基于使用核壳型 Cu@PtPd/C 纳米粒子修饰的玻璃碳复合电极的过氧化氢非酶促电流传感器。Cu@PtPd/C 对过氧化氢还原具有重要的电催化活性。在用 5.0% w/w Pt/C、Pd/C、Pd/C + Pt/C 和 Cu@PtPd/C 改性的玻碳复合电极上对过氧化氢的敏感性和电荷转移电阻的比较表明当 Pt、Pd 和 Cu 结合在核壳纳米结构中时，在 -0.100 V 下催化还原过氧化氢的协同作用。20.0% w/w Cu@PtPd/C 达到了灵敏度、重现性和响应时间之间的最佳折衷。对于选定的传感器（玻碳复合电极含有 20.