Abstract This study investigates synergistic hydrate inhibition performance of conventional thermodynamic hydrate inhibitors (THIs) combined with amino acids. For this purpose, hydrate-liquid-vapor equilibrium (HLVE) data for methane were measured in the presence of mixed ethylene glycol and glycine using 1:1 mixtures at concentrations of 1 wt% (0.5 wt% ethylene glycol +0.5 wt% glycine), 5 wt% (2.5 wt% ethylene glycol +2.5 wt% glycine), 10 wt% (5 wt% ethylene glycol +5 wt% glycine), 20 wt% (10 wt% ethylene glycol +10 wt% glycine), and 30 wt% (15 wt% ethylene glycol +15 wt% glycine) by the isochoric pressure search method. Thermodynamic inhibition efficiency has been investigated by observing the shifts in the hydrate equilibrium curves and trends of the calculated hydrate suppression temperatures at various concentrations and pressures. The results were also obtained for ethylene glycol, glycine and ionic liquids for comparison. An improving inhibition performance by mixing ethylene glycol and glycine was observed, indicating the potential of amino acids as inhibition synergists in hydrate exploitation, oil/gas transportation and flow assurance. Molar hydrate dissociation enthalpies were calculated by using the Clausius-Clapeyron equation and showed that the interaction of ethylene glycol and glycine has no impact on the hydrate structure.

中文翻译：

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乙二醇和甘氨酸混合物抑制甲烷水合物形成的性能

摘要 本研究调查了常规热力学水合物抑制剂 (THI) 与氨基酸组合的协同水合物抑制性能。为此，在混合乙二醇和甘氨酸存在下使用 1:1 混合物以 1 wt% 的浓度（0.5 wt% 乙二醇 +0.5 wt% 甘氨酸）测量甲烷的水合物-液体-蒸汽平衡 (HLVE) 数据、5wt%（2.5wt%乙二醇+2.5wt%甘氨酸）、10wt%（5wt%乙二醇+5wt%甘氨酸）、20wt%（10wt%乙二醇+10wt%甘氨酸），和30wt%（15wt%乙二醇+15wt%甘氨酸）通过等容压搜索法。通过观察不同浓度和压力下水合物平衡曲线的变化和计算出的水合物抑制温度的趋势，研究了热力学抑制效率。还获得了乙二醇、甘氨酸和离子液体的结果以进行比较。观察到通过混合乙二醇和甘氨酸改善抑制性能，表明氨基酸在水合物开采、油气运输和流动保证中作为抑制协同剂的潜力。使用克劳修斯-克拉佩龙方程计算摩尔水合物解离焓，结果表明乙二醇和甘氨酸的相互作用对水​​合物结构没有影响。