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Theobromine Does Not Affect Fasting and Postprandial HDL Cholesterol Efflux Capacity, While It Decreases Fasting miR‐92a Levels in Humans
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2018-06-19 , DOI: 10.1002/mnfr.201800027
Charlotte P.J. Talbot 1 , Ronald P. Mensink 1 , Lotte Smolders 1 , Virginie Bakeroot 1 , Jogchum Plat 1
Affiliation  

Chocolate consumption lowers cardiovascular disease risk, which might be attributed to the methylxanthine theobromine. These effects may be mediated through effects on HDL‐mediated cholesterol efflux, which may be affected by microRNA (miRNA) levels in the HDL particles. Therefore, the aim of this study is to investigate effects of theobromine consumption on fasting and postprandial cholesterol efflux and miRNAs levels.

中文翻译:

可可碱不会影响禁食和餐后HDL胆固醇外排量,但会降低人的禁食miR-92a水平。

食用巧克力可以降低心血管疾病的风险,这可能归因于甲基黄嘌呤可可碱。这些影响可能是通过对HDL介导的胆固醇外流的影响而介导的,而HDL颗粒中的microRNA(miRNA)水平可能会对其产生影响。因此,本研究的目的是研究可可碱消耗量对禁食和餐后胆固醇外流以及miRNA水平的影响。
更新日期:2018-06-19
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