Abstract We have synthesized a silicate bioactive glass-ceramic (BGC1) in the system SiO2-CaO-Na2O-P2O5-K2O-MgO-CaF2 which was used to fabricate pellets by powder compaction and sintering. The surface of BGC1 pellets was coated with polydopamine by using a simple immersion method. Silver nanoparticles were then deposited onto the surface of polydopamine modified pellets in order to confer antibacterial properties. The biomineralization ability was tested by soaking the samples in simulated body fluid (SBF). Results showed the successful deposition of both polydopamine and silver nanoparticles on the bioactive glass-ceramic surface. In addition, the formation of a hydroxyapatite layer (HA) on the surface of the samples after soaking them in SBF was confirmed. The kinetics of HA formation was minimally reduced by the presence of polydopamine.

中文翻译：

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熔体衍生的生物活性玻璃陶瓷上的含银聚多巴胺涂层：对表面反应性的影响

摘要 我们在SiO2-CaO-Na2O-P2O5-K2O-MgO-CaF2 体系中合成了一种硅酸盐生物活性微晶玻璃（BGC1），用于通过粉末压制和烧结来制造颗粒。通过使用简单的浸渍方法，BGC1 颗粒的表面被聚多巴胺包被。然后将银纳米颗粒沉积在聚多巴胺改性颗粒的表面上，以赋予抗菌性能。通过将样品浸泡在模拟体液（SBF）中来测试生物矿化能力。结果表明聚多巴胺和银纳米颗粒都成功沉积在生物活性玻璃陶瓷表面。此外，确认在将样品浸泡在 SBF 中后，在样品表面形成了羟基磷灰石层 (HA)。聚多巴胺的存在最大限度地降低了 HA 形成的动力学。