We previously reported the synthesis of BICMAP (1a) via 6-diphenylphosphino-2,3-dihydrobenzofuran as a key intermediate. However, we did not successfully synthesize BICMAP analogues via a similar synthetic route. Herein we report the second-generation synthesis of BICMAP and its derivatives via diethylphosphonate as a key intermediate.

中文翻译：

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BICMAP类似物的第二代合成

我们先前报道了通过6-二苯基膦-2,3-二氢苯并呋喃作为关键中间体合成BICMAP（1a）。但是，我们没有通过相似的合成途径成功合成BICMAP类似物。在本文中，我们报告了通过二乙基膦酸酯作为关键中间体的BICMAP及其衍生物的第二代合成。