Abstract Calcium phosphate cements are used as synthetic bone grafts with several advantages such as biocompatibility, osteoconductivity, and moldability. In this study, the synthesis of a biocement starting from calcium hydroxide (Ca(OH) 2 ) and Monocalcium Phosphate Monohydrate (MCPM) was investigated. A 6 wt% Na 2 HPO 4 aqueous solution along with a modified polymeric resin (RIVA(SDI) ® ) were adopted as the variable liquid phase in self- and light-cure cement groups. XRD analysis and FTIR spectroscopy were used to study the phase composition. The composite microstructure was characterized by scanning electron microscopy (SEM) and the degradation rates were measured by atomic absorption spectroscopy (AAS) analysis. In addition, the effect of soaking time of the cement in simulated body fluid (SBF) on the final phase and morphology was studied. The results showed that soaking the composite in SBF has a significant influence in phase transformation into hydroxyapatite, but following a slower kinetic in light-cured composite cements. Evidences of crosslinking reactions in light-cured cements were observable, which at the same time can legitimize slower apatite formation and faster biodegradation of these composite cements.

中文翻译：

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新型光固化复合磷酸钙水泥上磷灰石的体外形成和生长动力学

摘要 磷酸钙骨水泥被用作合成骨移植物，具有生物相容性、骨传导性和可塑性等几个优点。在这项研究中，研究了以氢氧化钙 (Ca(OH) 2 ) 和一水磷酸二氢钙 (MCPM) 为原料合成生物水泥。在自固化和光固化水泥组中，采用 6 wt% Na 2 HPO 4 水溶液和改性聚合物树脂 (RIVA(SDI) ® ) 作为可变液相。XRD分析和FTIR光谱用于研究相组成。通过扫描电子显微镜 (SEM) 表征复合材料的微观结构，并通过原子吸收光谱 (AAS) 分析测量降解率。此外，研究了水泥在模拟体液（SBF）中的浸泡时间对最终相和形态的影响。结果表明，将复合材料浸泡在 SBF 中对向羟基磷灰石的相转变有显着影响，但在光固化复合水泥中的动力学较慢。可以观察到光固化水泥中发生交联反应的证据，同时可以使这些复合水泥的较慢的磷灰石形成和较快的生物降解合法化。