Integration of Biomaterials into Sensors Based on Organic Thin‐Film Transistors,Macromolecular Rapid Communications

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Integration of Biomaterials into Sensors Based on Organic Thin‐Film Transistors
Macromolecular Rapid Communications ( IF 4.2 ) Pub Date : 2018-05-22 , DOI: 10.1002/marc.201800084
Xiaohan Wu ₁ , Jiachen Zhou ₁ , Jia Huang ₁

Affiliation

Sensors based on organic thin‐film transistors (OTFTs) present various advantages, including high sensitivity and mechanical flexibility, thus possessing potential applications such as wearable devices and biomedical electronics for health monitoring, etc. However, such applications are partially limited by the biocompatibility, biodegradability, and sensitivity to target analytes of OTFT‐based sensors, which can be improved by the incorporation of diverse biomaterials. This article presents a brief review from the viewpoint of the type of the integrated biomaterials, including naturally occurring biomacromolecules such as proteins, enzymes, and deoxyribonucleic acid, as well as biocompatible polymers such as polylactide, poly(lactide‐co‐glycolide), poly(ethylene glycol), cellulose, polydimethylsiloxane, parylene, etc. It is believed that future work in this field should be devoted to the selectivity, sensitivity, and stability improvement as well as the high‐level integration and sophistication on the basis of the OTFT‐based sensors for physical, chemical, and biological sensing applications.

中文翻译：

基于有机薄膜晶体管的生物材料到传感器的集成

基于有机薄膜晶体管（OTFT）的传感器具有多种优势，包括高灵敏度和机械柔韧性，因此具有潜在的应用，例如可穿戴设备和用于健康监测的生物医学电子产品等。但是，此类应用受到生物相容性的部分限制，可生物降解性，以及对基于OTFT的传感器的目标分析物的敏感性，可以通过掺入多种生物材料来提高。本文介绍从集成的生物材料，包括天然存在的生物大分子，如蛋白质，酶和脱氧核糖核酸，以及生物相容的聚合物如聚丙交酯，聚类型的观点出发，简要回顾（丙交酯-共乙交酯），聚（乙二醇），纤维素，聚二甲基硅氧烷，聚对二甲苯等。人们认为，该领域的未来工作应致力于选择性，灵敏度和稳定性的改进，以及高水平的集成度和复杂性。用于物理，化学和生物传感应用的基于OTFT的传感器的基础。

更新日期：2018-05-22

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