Many proteins possess functional attributes that make them suitable for the encapsulation of bioactive agents, such as nutraceuticals and pharmaceuticals. This article reviews the state of the art of protein‐based nanoencapsulation approaches. The physicochemical principles underlying the major techniques for the fabrication of nanoparticles, nanogels, and nanofibers from animal, botanical, and recombinant proteins are described. Protein modification approaches that can be used to extend their functionality in these nanocarrier systems are also described, including chemical, physical, and enzymatic treatments. The encapsulation, retention, protection, and release of bioactive agents in different protein‐based nanocarriers are discussed. Finally, some of the major challenges in the design and fabrication of protein‐based delivery systems are highlighted.

中文翻译：

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基于蛋白质的食品成分纳米封装递送系统

许多蛋白质具有使它们适合封装生物活性剂（如保健食品和药物）的功能属性。本文回顾了基于蛋白质的纳米封装方法的最新技术。描述了从动物，植物和重组蛋白制造纳米颗粒，纳米凝胶和纳米纤维的主要技术基础的物理化学原理。还描述了可用于在这些纳米载体系统中扩展其功能的蛋白质修饰方法，包括化学，物理和酶处理。讨论了在不同的基于蛋白质的纳米载体中生物活性剂的包封，保留，保护和释放。最后，