P-Arylation of secondary phosphine oxides catalyzed by nickel-supported nanoparticles†,Organic Chemistry Frontiers

当前位置： X-MOL 学术 › Org. Chem. Front. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

P-Arylation of secondary phosphine oxides catalyzed by nickel-supported nanoparticles†
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2018-05-22 00:00:00 , DOI: 10.1039/c8qo00356d
Elżbieta Łastawiecka _{1,

2,

3,

4,

5} , Anna Flis _{1,

2,

3,

4,

5} , Marek Stankevič _{1,

2,

3,

4,

5} , Magdalena Greluk _{2,

5,

6,

7,

8} , Grzegorz Słowik _{2,

5,

6,

7,

8} , Wojciech Gac _{2,

5,

6,

7,

8}

Affiliation

A protocol for the cross coupling of aryl halides with secondary phosphine oxides over Ni/CeO₂ or Ni/Al₂O₃ catalysts has been developed for the first time. The advantages offered using this protocol are operational simplicity and the use of an inexpensive heterogeneous nickel catalyst in the absence of any additional ligand. A range of aryl bromides and iodides are coupled with secondary phosphine oxides using low loadings of a catalyst (1 mol%) via this procedure, with good to high yield (up to 86%). Moreover, the influence of nickel particle size and catalyst support on P-arylation of secondary phosphine oxides has also been established.

中文翻译：

镍负载纳米粒子催化的次膦氧化物的P-芳基化作用†

首次开发了在Ni / CeO ₂或Ni / Al ₂ O ₃催化剂上使芳基卤化物与仲膦氧化物交叉偶联的方案。使用该协议提供的优点是操作简便，并且在没有任何其他配体的情况下使用便宜的异质镍催化剂。使用少量负载的催化剂（1 mol％），通过该程序，可以将一系列的芳基溴化物和碘化物与仲氧化膦偶联，并具有良好或较高的收率（高达86％）。此外，还已经确定了镍粒度和催化剂载体对仲膦氧化物的P-芳基化的影响。

更新日期：2018-05-22

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11