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Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts
International Journal of Epidemiology ( IF 6.4 ) Pub Date : 2018-05-19 , DOI: 10.1093/ije/dyy081
Yoshie Yokoyama 1 , Aline Jelenkovic 2, 3 , Yoon-Mi Hur 4 , Reijo Sund 2, 5 , Corrado Fagnani 6 , Maria A Stazi 6 , Sonia Brescianini 6 , Fuling Ji 7 , Feng Ning 7 , Zengchang Pang 7 , Ariel Knafo-Noam 8 , David Mankuta 9 , Lior Abramson 8 , Esther Rebato 3 , John L Hopper 10, 11 , Tessa L Cutler 10 , Kimberly J Saudino 12 , Tracy L Nelson 13 , Keith E Whitfield 14 , Robin P Corley 15 , Brooke M Huibregtse 15 , Catherine A Derom 16, 17 , Robert F Vlietinck 16 , Ruth J F Loos 18 , Clare H Llewellyn 19 , Abigail Fisher 19 , Morten Bjerregaard-Andersen 20, 21, 22 , Henning Beck-Nielsen 22 , Morten Sodemann 23 , Robert F Krueger 24 , Matt McGue 24 , Shandell Pahlen 24 , Meike Bartels 25 , Catharina E M van Beijsterveldt 25 , Gonneke Willemsen 25 , Jennifer R Harris 26 , Ingunn Brandt 26 , Thomas S Nilsen 26 , Jeffrey M Craig 27, 28 , Richard Saffery 27, 28 , Lise Dubois 29 , Michel Boivin 30, 31 , Mara Brendgen 32 , Ginette Dionne 30 , Frank Vitaro 33 , Claire M A Haworth 34 , Robert Plomin 35 , Gombojav Bayasgalan 36 , Danshiitsoodol Narandalai 36, 37 , Finn Rasmussen 38, 39 , Per Tynelius 38 , Adam D Tarnoki 40, 41 , David L Tarnoki 40, 41 , Syuichi Ooki 42 , Richard J Rose 43 , Kirsi H Pietiläinen 44, 45 , Thorkild I A Sørensen 46, 47 , Dorret I Boomsma 25 , Jaakko Kaprio 48, 49 , Karri Silventoinen 2, 50
Affiliation  

The genetic architecture of birth size may differ geographically and over time. We examined differences in the genetic and environmental contributions to birthweight, length and ponderal index (PI) across geographical-cultural regions (Europe, North America and Australia, and East Asia) and across birth cohorts, and how gestational age modifies these effects.

中文翻译:

影响出生体型变异的遗传和环境因素:使用 26 个双胞胎队列对长期趋势和全球地理差异进行基于个体的汇总分析

出生体型的遗传结构可能在地理上和时间上有所不同。我们检查了跨地理文化区域(欧洲、北美和澳大利亚以及东亚)和出生队列的遗传和环境对出生体重、身长和体重指数 (PI) 的贡献的差异,以及胎龄如何改变这些影响。
更新日期:2018-05-19
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