As fluorescent probes, the small Stokes shift and ACQ effect limit the application of BINOL derivatives. Herein, a new series of BINOL derivatives were synthesized which could be turned from ACQ to AIE fluorophores by changing the electron withdrawing group. Among these compounds, BIN-COP exhibits an obvious AIE property with low cytotoxicity. The bioimaging performance indicated that the designed fluorophores could be successfully used for bioimaging.

中文翻译：

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具有侵略性排放的BINOL衍生物†

作为荧光探针，小的斯托克斯位移和ACQ效应限制了BINOL衍生物的应用。本文合成了一系列新的BINOL衍生物，可通过改变吸电子基团将其从ACQ转变为AIE荧光团。在这些化合物中，BIN-COP表现出明显的AIE特性且细胞毒性低。生物成像性能表明所设计的荧光团可以成功用于生物成像。