SearchGUI: A Highly Adaptable Common Interface for Proteomics Search and de Novo Engines,Journal of Proteome Research

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SearchGUI: A Highly Adaptable Common Interface for Proteomics Search and de Novo Engines
Journal of Proteome Research ( IF 3.8 ) Pub Date : 2018-05-25 , DOI: 10.1021/acs.jproteome.8b00175
Harald Barsnes , Marc Vaudel ₁

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Mass-spectrometry-based proteomics has become the standard approach for identifying and quantifying proteins. A vital step consists of analyzing experimentally generated mass spectra to identify the underlying peptide sequences for later mapping to the originating proteins. We here present the latest developments in SearchGUI, a common open-source interface for the most frequently used freely available proteomics search and de novo engines that has evolved into a central component in numerous bioinformatics workflows.

中文翻译：

SearchGUI：用于蛋白质组学搜索和从头引擎的高度适应性通用接口

基于质谱的蛋白质组学已成为鉴定和定量蛋白质的标准方法。至关重要的步骤包括分析实验产生的质谱图，以识别潜在的肽序列，以供以后映射至起始蛋白。我们在此介绍SearchGUI的最新进展，SearchGUI是最常用的免费使用的蛋白质组学搜索和从头引擎的通用开源接口，现已演变为众多生物信息学工作流程中的核心组件。

更新日期：2018-05-27

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