As part of a bioprospecting program aimed at the discovery of anti-inflammatory agents from the Corydalis bungeana Turcz. (C. bungeana), five new hexahydrobenzophenanthridine alkaloids, corycaline A-E (1–5), along with four known alkaloids, were isolated from the whole plant of C. bungeana. Their structures including absolute configurations were elucidated on the basis of extensive spectroscopic analyses and electronic circular dichroism (ECD) calculations. The inhibitory activities of the nine compounds on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 mouse macrophage cells were determined; all tested compounds except 2 and 7 exhibited significant inhibitory effects with IC₅₀ values in the range of 1.00–2.79 μM.

作为生物勘探计划的一部分，该计划的目的是从延胡索木中提取抗炎药。（C.白皮松），五个新hexahydrobenzophenanthridine生物碱，corycaline AE（1 - 5）中，用四个已知生物碱一起，被从全植物中分离C.白皮松。在广泛的光谱分析和电子圆二色性（ECD）计算的基础上，阐明了它们的结构，包括绝对构型。确定了这9种化合物对RAW 264.7小鼠巨噬细胞中脂多糖（LPS）诱导的一氧化氮（NO）产生的抑制活性；除2和7外，所有测试的化合物表现出显着的抑制作用，IC ₅₀值在1.00–2.79μM的范围内。