Enzyme-driven biodegradable nanomotor based on tubular-shaped polymeric vesicles†,Polymer Chemistry

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Enzyme-driven biodegradable nanomotor based on tubular-shaped polymeric vesicles†
Polymer Chemistry ( IF 4.1 ) Pub Date : 2018-05-18 00:00:00 , DOI: 10.1039/c8py00559a
B. Jelle Toebes _{1,

2,

3,

4,

5} , Loai K. E. A. Abdelmohsen _{1,

2,

3,

4,

5} , Daniela A. Wilson _{1,

2,

3,

4,

5}

Affiliation

Various nanomotors that can mimic the motion of natural systems have recently been proposed. Yet, most designs are metal based and not applicable in biological settings. We report the first biodegradable nanomotor that moves in the presence of fuel. Tubular-shaped polymersomes with 5 wt% azide handles were assembled with catalase chemically linked to the handles. The nanotubes move autonomously in H₂O₂.

中文翻译：

基于管状聚合物囊泡的酶驱动可生物降解纳米马达†

最近已经提出了各种可以模仿自然系统运动的纳米马达。但是，大多数设计是基于金属的，不适用于生物环境。我们报告了第一个在燃料存在下移动的可生物降解的纳米马达。将具有5 wt％叠氮化物提手的管状聚合体与过氧化氢酶化学连接到提手上。纳米管在H ₂ O _2中自主移动。

更新日期：2018-05-18

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