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Shining a Light on Alport Syndrome
Cell Chemical Biology ( IF 6.6 ) Pub Date : 2018-05-17 , DOI: 10.1016/j.chembiol.2018.05.001
Lorna J. Hale , Melissa H. Little

In this issue ofCell Chemical Biology,Omachi et al. (2018)present a split Nanoluciferase system to identify successful protein trimerization in Alport syndrome. This elegant proof of concept suggests opportunities for drug screening for Alport syndrome and may be transferable to the study of other diseases affecting protein-protein interactions.

中文翻译:

照耀阿尔波特综合症

在本期《细胞化学生物学》中,Omachi等人。(2018)提出了一种分离的纳米荧光素酶系统,以鉴定Alport综合征中成功的蛋白质三聚化。这种精妙的概念证明为Alport综合征的药物筛查提供了机会,并且可以转移到影响蛋白质相互作用的其他疾病的研究中。
更新日期:2018-05-17
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